MEK/PI3K-IN-1

SKU: orb1983012

Description

MEK/PI3K-IN-1 (6r) is a dual MEK and PI3K inhibitor with IC50 values of 124 nM for MEK1 and 130/236 nM for PI3Kα/δ. It suppresses pERK and pAKT signaling, demonstrating anti-proliferative activity in cancer cell lines, which supports its use in oncology research for studying pathway crosstalk.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2281803-28-7
• MW: 913.63
• Formula: C₃₆H₃₇F₅IN₉O₆
• SMILES: FC(F)c1nc2ccccc2n1-c1nc(NCCOCCOCCOCCONC(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)nc(n1)N1CCOCC1
• Target: ERK,PI3K,MEK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163408817