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MEK-IN-6

SKU: orb1944374

Description

MEK-IN-6 (Example 69) is a highly potent and selective MEK inhibitor with an IC50 of 2 nM for inhibiting ERK1/2 phosphorylation in A375 melanoma cells. This compound is a valuable chemical probe for investigating the MAPK/ERK pathway in cancer research, supporting both in vitro cellular studies and in vivo preclinical models.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2845151-86-0
MW393.43
FormulaC18H20FN3O4S
SMILESN(C1=C2C(CCN(OCCO)C2=O)=CC(=O)N1C)C3=C(F)C=C(SC)C=C3
TargetERK,MEK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

MEK-IN-6 (orb1944374)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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