Me-(S,R,S)-AHPC-CO-C5-N3

SKU: orb2944566

Description

This conjugate, composed of a VHL-targeting ligand linked to an azide handle, serves as a key component for constructing PROTAC degraders like CG-167. It enables the targeted recruitment of the E3 ubiquitin ligase machinery in both cellular and in vivo models to induce protein degradation.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2590689-22-6
• MW: 583.745
• Formula: C₂₉H₄₁N₇O₄S
• SMILES: C([C@@H](NC(CCCCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@H](C(N[C@@H](C)C2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1
• Target: E3 Ligase Ligand-Linker Conjugates

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455416