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MDM2/4-p53-IN-2

SKU: orb1982488

Description

MDM2/4-p53-IN-2 (2q) is a dual MDM2 and MDM4 antagonist that potently disrupts their interactions with p53, with IC50 values of 70.7 nM and 81.4 nM, respectively. This reactivation of p53 function induces cell cycle arrest and apoptosis, supporting its investigation as a potential anticancer agent in both cellular and animal model studies.

Research Area

Cancer Biology; Cell Biology, Cell Biology

Images & Validation

Key Properties

MW532.78
FormulaC25H17Cl3FN3O3
TargetOthers,MDM-2/p53,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

MDM2/4-p53-IN-2 (orb1982488)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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