MDK8228

SKU: orb1699983

Description

MDK8228 is a dual bromodomain inhibitor targeting CBP/p300 and BRD4. It effectively suppresses pro-inflammatory cytokine production, including IL-6, IL-1β, and IFN-β, in macrophage models. This compound is a valuable chemical probe for epigenetic and immunology research in both cellular and animal studies of inflammation.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1962928-22-8
• MW: 531.69
• Formula: C₃₁H₄₁N₅O₃
• SMILES: C(CN1CCOCC1)N2C=3C(N=C2CCC4=CC=C(OCCCN(C)C)C=C4)=CC(=CC3)C=5C(C)=NOC5C
• Target: Epigenetic Reader Domain,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

121237857