MD-222

SKU: orb1693219

Description

MD-222 is a potent and innovative PROTAC degrader that targets MDM2 for rapid protein degradation, leading to wild-type p53 activation. This mechanism demonstrates significant anticancer activity in cellular studies, supporting its use in oncology research for investigating p53-mediated pathways in vitro.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Protein Biochemistry

Key Properties

• CAS Number: 2136246-72-3
• MW: 893.84
• Formula: C₄₈H₄₇Cl₂FN₆O₆
• SMILES: Fc1c(Cl)cccc1[C@H]1[C@@H](NC2(CCCCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12)C(=O)Nc1ccc(cc1)C(=O)NCCCCCc1cccc2C(=O)N(Cc12)C1CCC(=O)NC1=O
• Target: E1/E2/E3 Enzyme,PROTACs,MDM-2/p53

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

131988640