MCU-i4

SKU: orb1298430

Description

MCU-i4 is a small molecule inhibitor of the Mitochondrial Calcium Uniporter (MCU) that acts by binding to the regulatory protein MICU1. This negative modulation inhibits mitochondrial calcium uptake, a mechanism used in vitro to study calcium signaling and its impact on processes like muscle cell growth and metabolism.

Research Area

Metabolism Research

Key Properties

• CAS Number: 371924-24-2
• MW: 377.48
• Purity: 99.98% (May vary between batches)
• Formula: C₂₃H₂₇N₃O₂
• SMILES: CCOC(=O)c1cnc2ccc(C)cc2c1Nc1ccc(cc1)N(CC)CC
• Target: Mitochondrial Metabolism
• Solubility: DMSO:21.67 mg/mL (57.41 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

uptake, MCU i4, MCUi4, MCU-i4, MCU-i-4, MCU, mitochondrial, Mitochondrial Metabolism, MitochondrialMetabolism, myoblast, Inhibitor, inhibit, C2C12, Ca2+

Compound Identifiers

PubChem CID

1568449