(+)-Mcl-1 inhibitor 22

SKU: orb2945549

Description

(+)-Mcl-1 inhibitor 22 (Example 37) is a potent and selective small molecule that disrupts MCL-1's interaction with pro-apoptotic proteins, inducing apoptosis. It exhibits robust anti-proliferative activity in diverse cancer cell lines in vitro and has shown efficacy in xenograft tumor models in vivo, supporting its use in oncology research.

Research Area

Cell Biology, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 2332611-98-8
• MW: 590.084
• Formula: C₃₃H₃₃ClFN₃O₄
• SMILES: O=C(O)C1=C(C=2C=CC(Cl)=C3C=4C(=NN(C4CC)C)COCCCCN1C23)CCCOC5=CC=CC=6C=C(F)C=CC56
• Target: Apoptosis,Bcl-2 Family

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

142591175