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Mcl-1-IN-17

SKU: orb3173474

Description

Mcl-1-IN-17 (Compound 25) is an orally active inhibitor of myeloid cell leukemia 1 protein (Mcl-1), with a Ki of less than 0.08 nM. It exhibits significant antiproliferative activity with GI50 values of 39 nM in H929 cells and 105 nM in A427 cells, and it inhibits apoptosis. This compound is suitable for research in hematological and solid tumors.

Research Area

Cell Biology

Images & Validation

Key Properties

TargetBcl-2 Family,Apoptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information