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Catalog Number | orb2278619 |
---|---|
Category | Small Molecules |
Description | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1), it demonstrates increased specificity against collagenases (MMP-1, MMP-8, MMP-13) and MT1-MMP, with higher specificity constants (Ex/Em=325 nm/400 nm). [1] |
CAS Number | 720710-69-0 |
Purity | 98.00% |
MW | 1221.32 |
SMILES | C(C(N[C@H](C(=O)N1[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CNC2=C(N(=O)=O)C=C(N(=O)=O)C=C2)C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)C)=O)=O)CC(C)C)=O)=O)CC(C)C)=O)CCC1)CCCCN)=O)C=3C=4C(=CC(OC)=CC4)OC(=O)C3 |
Formula | C55H80N16O16 |
Biological Activity | Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic activity. As an extended variant of the MMP substrate (FS-1), it demonstrates increased specificity against collagenases (MMP-1, MMP-8, MMP-13) and MT1-MMP, evidenced by higher specificity constants (Ex/Em=325 nm/400 nm). [1] |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |