MC3343

SKU: orb2814381

Description

MC3343 is a dual DNMT inhibitor (IC50: 5.7 µM for DNMT1, 1.7 µM for DNMT3a) that arrests osteosarcoma cell cycle progression and induces osteogenic differentiation. It demonstrates synergistic anti-proliferative effects with adriamycin and cisplatin in vitro, supporting its research use in cancer epigenetics and combination therapy studies.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 1535187-91-7
• MW: 461.52
• Purity: 99.73%
• Formula: C₂₇H₂₃N₇O
• SMILES: O=C(NC=1C=CC=C(C1)NC2=NC(=NC(=C2)C)N)C=3C=CC=C(C3)NC=4C=CN=C5C=CC=CC54
• Target: DNA Methyltransferase

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MC 3343

Compound Identifiers

PubChem CID

76318201