MC-VC-PAB-Cyclohexanediamine-Thailanstatin A

• Catalog Number: orb2278203
• Category: Small Molecules
• Description: MC-VC-PAB-Cyclohexanediamine-Thailanstatin A, a spliceostatin analog and drug-linker conjugate for antibody-drug conjugates (ADC), comprises the cytotoxic component Thailanstatin A and the cleavable linker (MC-vc-PAB). This compound is utilized in the synthesis of ADCs [1].
• CAS Number: 1609108-96-4
• Purity: 98.00%
• MW: 1230.45
• SMILES: O[C@H]1[C@]2(CO2)C[C@@H](CC(N[C@@H]3CC[C@@H](NC(OCC4=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN5C(=O)C=CC5=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C4)=O)CC3)=O)O[C@@H]1/C=C/C(=C/C[C@H]6[C@@H](C)C[C@@H](NC(/C=C\[C@@H](OC(C)=O)C)=O)[C@@H](C)O6)/C
• Formula: C₆₃H₉₁N₉O₁₆
• Biological Activity: MC-VC-PAB-Cyclohexanediamine-Thailanstatin A is a spliceostatin analog and a drug-linker conjugate for antibody-drug conjugates (ADC), comprising the cytotoxic component Thailanstatin A and the cleavable linker (MC-vc-PAB). This compound is utilized in the synthesis of ADCs [1].
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.