MC-Val-Cit-PAB-dimethylDNA31

• Catalog Number: orb1988050
• Category: Small Molecules
• Description: MC-Val-Cit-PAB-dimethylDNA31 is a drug-linker conjugate employed in antibody-drug conjugates (ADCs) that exhibits robust antitumor efficacy. This conjugate utilizes the ADC linker, MC-Val-Cit-PAB, to connect with the potent antitumor agent dimethylDNA31, which also demonstrates significant bactericidal activity against both persister and stationary-phase [Staphylococcus aureus].
• Target: Drug-Linker Conjugates for ADC
• MW: 1482.69
• CAS Number: 1639352-06-9
• Formula: C₇₈H₁₀₁N₁₀O₁₉
• SMILES: O=C1C=2C=3C=4C(=C5C(=O)C3C(O)=C(C)C2O[C@]1(C)O/C=C\[C@](OC)([C@@H](C)[C@@H](OC(C)=O)[C@H](C)[C@H](O)[C@H](C)[C@@H](O)[C@@H](C)\C=C\C=C(/C)\C(=O)N5)[H])OC=6C(N4)=C(O)C=C(C6)N7CCC([N+](CC8=CC=C(NC([C@@H](NC([C@@H](NC(CCCCCN9C(=O)C=CC9=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C8)(C)C)CC7
• Storage: -20°C
• Note: For research use only