MC-Gly-Gly-Phe

SKU: orb1307361

Description

MC-Gly-Gly-Phe is a cleavable peptide linker designed for constructing antibody-drug conjugates (ADCs). Its protease-sensitive sequence enables targeted drug release in both in vitro and in vivo research models, facilitating the study of ADC stability and efficacy in oncology research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1599440-15-9
• MW: 472.49
• Purity: 99.63%
• Formula: C₂₃H₂₈N₄O₇
• SMILES: C([C@H](NC(CNC(CNC(CCCCCN1C(=O)C=CC1=O)=O)=O)=O)C(O)=O)C2=CC=CC=C2
• Target: ADC Linker,PROTAC Linker
• Solubility: DMSO:49 mg/mL (103.71 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cleavable, Antibody-drug conjugates linkers, ADC Linker, ADCLinker, ADC Linkers, Inhibitor, inhibit, MC Gly Gly Phe, MCGlyGlyPhe, MC-Gly-Gly-Phe

Compound Identifiers

PubChem CID

118305216