Mc-Gly-Gly-Phe-Gly-PAB-OH

SKU: orb1984523

Description

This cleavable peptide linker, Mc-Gly-Gly-Phe-Gly-PAB-OH, is designed for constructing antibody-drug conjugates (ADCs). It enables targeted drug delivery and controlled payload release, facilitating research in ADC development for both in vitro and in vivo oncology studies.

Key Properties

• CAS Number: 2632342-05-1
• MW: 634.68
• Purity: 97.38% (May vary between batches)
• Formula: C₃₂H₃₈N₆O₈
• SMILES: [C@H](CC1=CC=CC=C1)(C(NCC(NC2=CC=C(CO)C=C2)=O)=O)NC(CNC(CNC(CCCCCN3C(=O)C=CC3=O)=O)=O)=O
• Target: ADC Linker
• Solubility: DMSO:200 mg/mL (315.12 mM)

Bioactivity

• In Vitro:
  ADCs consist of an antibody linked to an ADC cytotoxin via an ADC linker.

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADCLinker, ADC Linker, Mc-GGFG-PAB-OH, McGlyGlyPheGlyPABOH, Mc-Gly-Gly-Phe-Gly-PAB-OH, Mc Gly Gly Phe Gly PAB OH

Compound Identifiers

PubChem CID

146673133