MC-Gly-Gly-Phe-Gly-GABA-Exatecan

SKU: orb2564842

Description

MC-Gly-Gly-Phe-Gly-GABA-Exatecan is a bifunctional agent combining an ADC linker with the topoisomerase I inhibitor Exatecan. It demonstrates cytotoxic and antitumor activity in both in vitro and in vivo models, with an IC50 of 22 µM, and is designed for targeted antibody conjugation in cancer research.

Research Area

Molecular Biology, Neuroscience; Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1599439-52-7
• MW: 1032.08
• Formula: C₅₃H₅₈FN₉O₁₂
• SMILES: N(C(CCCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CNC(CCCCCN2C(=O)C=CC2=O)=O)=O)=O)=O)=O)=O)[C@@H]3C4=C5C(C=6N(C5)C(=O)C7=C(C6)[C@](CC)(O)C(=O)OC7)=NC=8C4=C(CC3)C(C)=C(F)C8
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

118305115