MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan

SKU: orb1982681

Description

MC-Gly-Gly-Phe-Gly-(S)-Cyclopropane-Exatecan is an antibody-drug conjugate (ADC) linker-payload featuring the topoisomerase I inhibitor Exatecan (IC50 = 2.2 µM). This conjugate is designed for targeted delivery in oncology research, enabling the study of Exatecan's cytotoxic effects in both in vitro and in vivo experimental models for cancer therapeutics.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2414254-52-5
• MW: 1074.12
• Formula: C₅₅H₆₀FN₉O₁₃
• SMILES: CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc(F)c(C)c5CC[C@H](NC(=O)[C@@H](OCNC(=O)CNC(=O)[C@H](Cc6ccccc6)NC(=O)CNC(=O)CNC(=O)CCCCCN6C(=O)C=CC6=O)C6CC6)c(c3Cn1c2=O)c45
• Target: Drug-Linker Conjugates for ADC,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146534317