MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan

SKU: orb2279076

Description

MC-Gly-Gly-Phe-Gly-Cyclobutanecarboxylic-Exatecan is an antibody-drug conjugate (ADC) linker-payload conjugate, combining a protease-cleavable peptide linker with the potent topoisomerase I inhibitor Exatecan. It is used in cancer research for developing ADCs, with applications in both in vitro cytotoxicity assays and in vivo xenograft studies to evaluate targeted tumor efficacy.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2414393-22-7
• MW: 1074.12
• Formula: C₅₅H₆₀FN₉O₁₃
• SMILES: N(C(=O)C1(OCNC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(CCCCCN3C(=O)C=CC3=O)=O)=O)=O)=O)=O)CCC1)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146505747