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MC-betaglucuronide-MMAE-2

SKU: orb1942931

Description

MC-betaglucuronide-MMAE-2 is a cleavable antibody-drug conjugate (ADC) featuring the cytotoxic payload MMAE, a potent tubulin polymerization inhibitor. This conjugate is a valuable research tool for investigating targeted cancer therapies, demonstrating significant antitumor activity in both in vitro and in vivo preclinical models.

Images & Validation

Key Properties

CAS Number1703778-81-7
MW1296.46
FormulaC63H93N9O20
SMILES[C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC(NC(CCNC([C@H](CN)N4C(=O)C=CC4=O)=O)=O)=C(O[C@@H]5O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]5O)C=C3)=O)C)C(C)C)=O)[C@H](C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
TargetDrug-Linker Conjugates for ADC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

MC-betaglucuronide-MMAE-2 (orb1942931)

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