MC-betaglucuronide-MMAE-1

SKU: orb1984711

Description

MC-betaglucuronide-MMAE-1 is a cleavable linker-drug conjugate for constructing antibody-drug conjugates (ADCs). Its payload, MMAE, inhibits tubulin polymerization, enabling potent antitumor activity. This conjugate is utilized in ADC research for both in vitro cytotoxicity assays and in vivo efficacy studies in preclinical cancer models.

Key Properties

• CAS Number: 1703778-92-0
• MW: 1323.546
• Formula: C₆₆H₉₈N₈O₂₀
• SMILES: CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)c(NC(=O)CCNC(=O)CCCCCN2C(=O)C=CC2=O)c1)C(C)C
• Target: Drug-Linker Conjugates for ADC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122647277