MC-25B

SKU: orb2944659

Description

MC-25B is a potent and selective PROTAC degrader of FKBP12, achieving 89% maximal degradation with a DC50 of 0.35 µM. Its DCAF16-dependent mechanism effectively targets nuclear FKBP12, making it a valuable chemical probe for studying FKBP12 biology in proteolysis-targeting chimera and molecular glue research, applicable in both cellular and biochemical assays.

Research Area

Cell Biology, Immunology & Inflammation

Key Properties

• MW: 1230.92
• Formula: C₆₅H₉₂ClN₇O₁₄
• Target: FKBP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

FKBP