MC-1-F2

SKU: orb1739821

Description

MC-1-F2 is a small molecule FOXC2 inhibitor that suppresses cancer stem cell properties and invasion in castration-resistant prostate cancer models. It is a useful research tool for studying prostate cancer mechanisms and evaluating potential therapeutic strategies in both cellular and animal studies.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2376894-10-7
• MW: 746.87
• Purity: 99.99% (May vary between batches)
• Formula: C₃₇H₄₆N₁₆O₂
• SMILES: N=C(N)NCCCCNC1=NC(=NC(=N1)N2CCN(C=3N=C(N=C(N3)NC4=CC=C(C=C4)N5CCOCC5)N)CC2)NC6=CC=C(OC=7C=CC=CC7)C=C6
• Target: Cadherin,Others,c-Myc
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (4.42 mM);DMSO:80 mg/mL (107.11 mM)

Bioactivity

• In Vitro:
  In PC3 or DU145 cell lines after treatment with DMSO (D), MC-1-F2 (F2, 20 µM) or MC-C2 (C, 20 µM) for 48 hours. A clear decrease in FOXC2 protein level upon 48-hour treatment with MC-1-F2.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139519325