MBM-17

SKU: orb1709185

Description

MBM-17 is a highly potent and selective Nek2 kinase inhibitor (IC50 = 3 nM). It suppresses cancer cell proliferation by triggering cell cycle arrest and apoptosis, making it a valuable chemical probe for oncology research in both cellular and animal models of tumorigenesis.

Research Area

Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2083621-90-1
• MW: 480.56
• Formula: C₂₈H₂₈N₆O₂
• SMILES: O(CC1=CC=CC=C1)C=2C=C(C=3N4C(C=C(C=C4)C5=CN(CCN(C)C)N=C5)=NC3)C=CC2C(N)=O
• Target: Apoptosis,MAPK,Aurora Kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137637358