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MAT2A-IN-24

SKU: orb3028398

Description

MAT2A-IN-24 (Compound 9) is an inhibitor of methionine adenosyltransferase 2a (MAT2a), with an IC50 value of 20 nM for MAT2a inhibition and an antiproliferative IC50 value of 10 nM for HAP1MTAP–/– cells. MAT2A-IN-24 is applicable in the research of tumor diseases associated with MTAP deficiency.

Research Area

Epigenetics & Chromatin, Signal Transduction

Images & Validation

Key Properties

CAS Number3031093-57-6
MW618.556
FormulaC32H33Cl2N7O2
SMILESO=C1N=C(C=2C=CC(Cl)=CC2N1C3=CC=CC(=C3)N4CCC(CN5C(=O)N=C(C=6C=CC(Cl)=CC65)N(C)C)CC4)N(C)C
TargetMethionine Adenosyltransferase (MAT)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information