MAT2A-IN-13

SKU: orb2565822

Description

MAT2A-IN-13 is an orally bioavailable, potent inhibitor of methionine adenosyltransferase 2A (MAT2A). It shows promising in vivo efficacy in MTAP-deleted xenograft models, supporting its use as a research tool for investigating synthetic lethality in MTAP-deficient cancers.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2851449-24-4
• MW: 364.3
• Formula: C₁₇H₁₂F₄N₄O
• SMILES: O=C1C(=C2N(C(NC3CC3)=N1)C=CC(C(F)(F)F)=C2)C4=C(F)N=CC=C4
• Target: Methionine Adenosyltransferase (MAT)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

169494477