MAT2A-IN-10

SKU: orb1944409

Description

MAT2A-IN-10 (Compound 28) is a potent, orally bioavailable MAT2A inhibitor with an IC50 of 26 nM. It is a valuable chemical probe for cancer research, particularly in studying methionine metabolism and its role in MTAP-deleted cancers in both cellular and animal models.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2924825-23-8
• MW: 534.51
• Formula: C₂₇H₂₄F₂N₆O₄
• SMILES: O=C1N(C=2C(C(=O)N1C=3C=C4N5C(=NC4=CC3)CN(C)CC5)=CC=C(OCC)N2)C6=CC=C(OC(F)F)C=C6
• Target: Methionine Adenosyltransferase (MAT)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168355483