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MART-1 (26-35) human

SKU: orb1220313

Description

MART-1 (26-35) human is amino acid residue 26 to 35 of MART-1 protein.

Images & Validation

Key Properties

CAS Number156251-01-3
MW943.1
Purity>98% (HPLC)
FormulaC42H74N10O14
SMILESCCC(C)C(NC(=O)CNC(=O)C(C)NC(=O)C(C)NC(=O)C(N)CCC(=O)O)C(=O)NCC(=O)NC(C(=O)NC(CC(C)C)C(=O)NC(C(=O)NC(C(=O)O)C(C)C)C(C)O)C(C)CC
TargetOthers

Bioactivity

In Vitro
MART-1 (Melan-A) gene is 18 kb long and comprises five exons. It is expressed in most melanoma tumor samples, and among normal cells, only in melanocytes. In cancer immunotherapy, epitopes and variants derived from the MART-1/Melan-A protein are widely used as clinical vaccines. The epitopes spanning amino acid residues 26-35 and 27-35 from the MART-1/Melan-A protein, highly expressed in melanoma cells, provide a prime example of T cell recognition of multiple peptides and the use of peptide variants designed to elicit altered immunological responses.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

MART-1 (26-35) human (orb1220313)

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