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marmesin

SKU: orb1220775

Description

Marmesin is a coumarin originally isolated from the mature bark of A. marmelosexhibiting COX-2/5-LOX dual inhibitory activity.

Images & Validation

Key Properties

CAS Number13849-08-6
MW246.26
Purity>98% (HPLC)
FormulaC14H14O4
SMILESCC(C)(O)[C@@H]1Cc2cc3ccc(=O)oc3cc2O1
TargetLipoxygenase
SolubilityDMSO:2 mg/mL (8.12 mM)

Bioactivity

In Vitro
S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(+)-Marmesin | (S)-Marmesin

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