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Maresin 1

SKU: orb1984918

Description

Maresin 1 is a specialized pro-resolving mediator biosynthesized by macrophages, demonstrating potent anti-inflammatory and pro-resolving actions. It attenuates LPS-induced lung injury in murine models by inhibiting neutrophil adhesion and reducing pro-inflammatory cytokines, while also stimulating intracellular Ca2+ signaling. This molecule is a valuable research tool for studying inflammation resolution mechanisms in both in vitro and in vivo contexts.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number1268720-28-0
MW360.49
FormulaC22H32O4
SMILES[C@H](/C=C/C=C/C=C\[C@H](C/C=C\C/C=C\CC)O)(C/C=C\CCC(O)=O)O
TargetCalcium Channel,Reactive Oxygen Species

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

Maresin 1 (orb1984918)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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% DMSO +
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% Tween 80 +
%

Available Sizes

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10 μg (277.4 μM x 100 μl in ethanol)
100 μg (277.4 μM x 1 ml in ethanol)
25 μg (277.4 μM x 250 μl in ethanol)
50 μg (277.4 μM x 500 μl in ethanol)