Marbofloxacin

SKU: orb1304519

Description

Marbofloxacin (Zeniquin) is a broad-spectrum fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, thereby blocking DNA replication. It is widely used in veterinary research for in vitro susceptibility testing and in vivo models of bacterial infections.

Research Area

Infectious Disease & Virology, Molecular Biology

Key Properties

• CAS Number: 115550-35-1
• MW: 362.36
• Purity: 99.98% (May vary between batches)
• Formula: C₁₇H₁₉FN₄O₄
• SMILES: O=C1C=2C3=C(C(=C(F)C2)N4CCN(C)CC4)OCN(C)N3C=C1C(O)=O
• Target: Antibacterial,Topoisomerase,Antibiotic
• Solubility: DMSO:2.18 mg/mL (6.02 mM)

Bioactivity

• In Vivo:
  Marbofloxacin treatment at the therapeutic dose does not eliminate M. hyopneumoniae, with 87.5 to 100% of the pigs still positive at the end of the assays, and is not effective in significantly reducing clinical signs. Nevertheless, Marbofloxacin treatment seems to decrease the lung lesion scores. Administration of Marbofloxacin at 6 mg/kg once daily for 7 days in a Staphylococcus aureus infection in tissue cages in ponies is not effective for the elimination of S. aureus infections from secluded sites.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

antimicrobial, Antibiotic, Bacterial, bacteria, Gram-negative, Gram-positive, fluoroquinolone, Marbocyl, Marbofloxacin, Marbofloxacine, Inhibitor, inhibit, Mycoplasma, Topo IV, Topo II, Zeniquin

Compound Identifiers

PubChem CID

60651