MAPK-IN-6

SKU: orb3175139

Description

MAPK-IN-6 (compound 116B) is a blood-brain barrier-penetrating compound that inhibits the MAPK signaling pathway. It reduces oxidative stress in SH-SY5Y neuronal cells by decreasing reactive oxygen species (ROS), restoring mitochondrial function, and inhibiting MAPK-driven inflammatory responses. In the tBCCAO/R rat model, MAPK-IN-6 exerts neuroprotective effects via the ERK-P38-JNK signaling pathway. It can be used as a neuroprotective agent in ischemic stroke research.

Key Properties

• Target: JNK,Mitochondrial Metabolism,ROS,ERK,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

JNK,Mitochondrial Metabolism,ROS,ERK,p38 MAPK