Manassantin B

SKU: orb1682165

Description

Manassantin B is a potent small molecule inhibitor of NF-κB and STAT3 signaling pathways, suppressing inflammation and fibrosis. It demonstrates anti-EBV lytic replication activity and has shown potential in research models for sepsis, acute lung injury, and hepatic fibrosis through in vitro studies in cell lines like Hep3B and HSC-T6.

Research Area

Cell Biology, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 88497-88-5
• MW: 716.81
• Formula: C₄₁H₄₈O₁₁
• SMILES: C[C@H]1[C@](O[C@@]([C@@H]1C)(C2=CC(OC)=C(O[C@@H]([C@H](O)C=3C=C4C(=CC3)OCO4)C)C=C2)[H])(C5=CC(OC)=C(O[C@@H]([C@H](O)C6=CC(OC)=C(OC)C=C6)C)C=C5)[H]
• Target: Antifection,TNF,ERK,p38 MAPK,NF-κB,STAT,Bcl-2 Family,JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

10439828