Managlinat dialanetil

SKU: orb1945051

Description

Managlinat dialanetil (MB06322) is a potent, orally administered inhibitor of fructose-1,6-bisphosphatase (FBPase). By suppressing hepatic gluconeogenesis, it demonstrates hypoglycemic effects, making it a valuable tool for in vitro and in vivo research into type 2 diabetes and metabolic disorders.

Research Area

Metabolism Research

Key Properties

• CAS Number: 280782-97-0
• MW: 500.55
• Purity: 98.82%
• Formula: C₂₁H₃₃N₄O₆PS
• SMILES: C(C(C)C)C1=C(N=C(N)S1)C=2OC(P(N[C@H](C(OCC)=O)C)(N[C@H](C(OCC)=O)C)=O)=CC2
• Target: Phosphatase
• Solubility: DMSO:20 mg/mL (39.96 mM)

Bioactivity

• In Vivo:
  Dose-dependently inhibiting gluconeogenesis (GNG), managlinat dialanetil also lowers basal and postprandial blood glucose levels in Zucker diabetic fatty (ZDF) rats after oral administration.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CS-917, Fructose-1,6-bisphosphate (FBPase), MB06322, MB 6322

Compound Identifiers

PubChem CID

9811837