Mal-PEG8-Phe-Lys-PAB-Exatecan

SKU: orb1942894

Description

This ADC features the cleavable Mal-PEG8-Phe-Lys-PAB linker conjugated to the potent topoisomerase I inhibitor Exatecan. It is a research tool for developing targeted cancer therapies and has been utilized in both in vitro cytotoxicity assays and in vivo xenograft model studies.

Research Area

Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2679821-44-2
• MW: 1434.56
• Formula: C₇₃H₉₂FN₉O₂₀
• SMILES: N(C(OCC1=CC=C(NC([C@@H](NC([C@H](CC2=CC=CC=C2)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCN3C(=O)C=CC3=O)=O)=O)=O)CCCCN)=O)C=C1)=O)[C@@H]4C5=C6C(C=7N(C6)C(=O)C8=C(C7)[C@](CC)(O)C(=O)OC8)=NC=9C5=C(CC4)C(C)=C(F)C9
• Target: Drug-Linker Conjugates for ADC,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165437243