Mal-PEG4-Val-Cit-PAB-MMAE

SKU: orb2814335

Description

This compound is the cleavable linker-payload component of antibody-drug conjugates (ADCs), comprising a Val-Cit-PAB protease-sensitive linker attached to the cytotoxic agent MMAE. It is widely used in ADC research for targeted cancer therapy, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• MW: 1450.76
• Purity: 99.14% (May vary between batches)
• Formula: C₇₃H₁₁₅N₁₁O₁₉
• SMILES: CC[C@@H](C(N([C@H](C(NC([C@H](C(C)C)N(C(OCC1=CC=C(NC([C@@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCN2C(C=CC2=O)=O)=O)=O)=O)C=C1)=O)C)=O)=O)C(C)C)C)[C@H](OC)CC(N3CCC[C@H]3C([C@H](C(N[C@@H]([C@H](C4=CC=CC=C4)O)C)=O)C)OC)=O)C
• Target: Drug-Linker Conjugates for ADC,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455333