MAL-di-EG-Val-Cit-PAB-MMAF

SKU: orb1988109

Description

This product is a conjugate of the protease-cleavable linker MAL-di-EG-Val-Cit-PAB and the cytotoxic payload MMAF (Monomethyl auristatin F). It is widely used in ADC (Antibody-Drug Conjugate) research for targeted cancer therapy, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• MW: 1476.75
• Formula: C₇₃H₁₁₃N₁₃O₁₉
• SMILES: CN([C@H](C(N[C@H](C(N([C@H]([C@@H](CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)=O)OC)[C@H](CC)C)C)=O)C(C)C)=O)C(C)C)N(C)C(OCC3=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCNC(CCN4C(C=CC4=O)=O)=O)=O)=O)=O)C=C3)=O
• Target: Drug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138911349