Mal-C6-α-Amanitin

SKU: orb1988110

Description

Mal-C6-α-Amanitin is an ADC linker-drug conjugate that delivers the potent RNA polymerase II inhibitor α-Amanitin to target cells. This construct enables research into targeted cancer therapies, demonstrating significant antitumor activity in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1578249-76-9
• MW: 1211.34
• Formula: C₅₅H₇₈N₁₂O₁₇S
• SMILES: [H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CS(=O)c3[nH]c4cc(OCCCCCCNC(=O)CCCCCN5C(=O)C=CC5=O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1
• Target: Drug-Linker Conjugates for ADC,PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

145712368