Mal-amido-PEG2-NHS ester

SKU: orb1909351

Description

Mal-amido-PEG2-NHS ester is a heterobifunctional, non-cleavable linker for constructing stable antibody-drug conjugates (ADCs). Its maleimide group targets cysteine thiols on antibodies, while the NHS ester reacts with primary amines on payloads like toxins or fluorescent dyes, enabling applications in targeted cancer therapy and biochemical research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 955094-26-5
• MW: 425.39
• Formula: C₁₈H₂₃N₃O₉
• SMILES: O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCC(=O)ON1C(=O)CCC1=O
• Target: ADC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

51340948