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MAK683-CH2CH2COOH

SKU: orb1707907

Description

MAK683-CH2CH2COOH is a ligand that binds the EED protein. When conjugated to a VHL ligand, it forms PROTAC degraders such as EED degrader-1 and -2, which are used in epigenetic and oncology research to study EED function and degradation in vitro.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2639882-68-9
MW448.45
FormulaC23H21FN6O3
SMILESN(CC1=C2C(OCC2)=CC=C1F)C=3N4C(C(=CN3)C5=C(C)N=C(CCC(O)=O)C=C5)=NN=C4
TargetHistone Methyltransferase,Others,Ligands for Target Protein for PROTAC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information