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MAGL-IN-22

SKU: orb3136811

Description

MAGL-IN-22 (Compound 40) is a reversible, competitive, and selective inhibitor of MAGL that is capable of crossing the blood-brain barrier, with an IC50 of 0.34 μM for hMAGL. It exhibits significant antioxidant and anti-inflammatory properties, activating the Nrf2 pathway and markedly suppressing NFκB-mediated inflammation, without inducing cytotoxic effects. MAGL-IN-22 is applicable in research on neurodegenerative diseases, chronic pain, and cancer.

Research Area

Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number2720674-71-3
MW365.40
FormulaC22H20FNO3
SMILESO=C(NC1=CC(=CC=C1O)C=2C=CC(O)=C(F)C2)CCCC=3C=CC=CC3
TargetNrf2,MAGL,NF-κB

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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MAGL-IN-22 (orb3136811)

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