Macrophage / Histiocytoma Marker Antibody

• Catalog Number: orb749974
• Category: Antibodies
• Description: In Western blotting, it detects an antigen of 125kDa in human liver and 135kDa in tumors of histiocytic origin. Comparative study of this mAb and a standard CD68 mAb showed that their antigens are different. Its antigen in all macrophage types studied is located on the plasma membrane and within cytoplasmic structures including lysosomes. This mAb shows a restricted reactivity to cells of the monocyte/macrophage system. It specifically reacts with blood monocytes and stains resident macrophages in a wide variety of human tissues. This mAb does not stain antigen-presenting cells, e.g., Langerhans cells. Reportedly, its reactivity is restricted to histiocytes and macrophages.
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: Mouse IgG1, kappa
• Conjugation: Unconjugated
• Reactivity: Human, Rat
• Immunogen: A membrane preparation from human hepatocytes was used as the immunogen for the Macrophage / Histiocytoma Marker antibody.
• UniProt ID: Not Known
• Tested applications: IHC-P
• Dilution range: Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
• Application notes: Optimal dilution of the SCLC Marker antibody should be determined by the researcher.
• Antibody Type: Primary Antibody
• Clone Number: D11
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Hazard Information: This Macrophage / Histiocytoma Marker antibody is available for research use only.
• Note: For research use only

IHC: Formalin-fixed, paraffin-embedded human Histiocytoma stained with Macrophage antibody (D11).

IHC: Formalin-fixed, paraffin-embedded human Histiocytoma stained with Macrophage antibody (D11).