Macitentan (n-butyl analogue)

• Catalog Number: orb1709204
• Category: Small Molecules
• Description: Macitentan (n-butyl analogue)
• Purity: 98.00%
• MW: 587.29
• Biological Activity: Macitentan n-butyl analogue, a derivative of Macitentan, functions as an orally active dual antagonist targeting both endothelin ETA and ETB receptors. This compound shows promise for treating idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH), leveraging its non-peptide structure for potential therapeutic applications.
• CAS Number: 556797-16-1
• Formula: C₂₀H₂₁Br₂N₅O₄S
• SMILES: CCCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1
• Storage: -20°C
• Note: For research use only