Macitentan-d4

SKU: orb1992793

Description

Macitentan-d4 is a deuterated analog of the dual endothelin receptor antagonist Macitentan. Its improved metabolic stability and reduced toxicity make it a valuable tool for investigating endothelin-mediated pathways in pulmonary arterial hypertension and other fibrotic diseases, both in vitro and in vivo.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1258428-05-5
• MW: 592.3
• Purity: 98.20% (May vary between batches)
• Formula: C₁₉H₂₀Br₂N₆O₄S
• SMILES: N(S(NCCC)(=O)=O)C=1C(=C(OC(C(OC=2N=CC(Br)=CN2)([2H])[2H])([2H])[2H])N=CN1)C3=CC=C(Br)C=C3
• Target: Endothelin Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

49849030