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M50054

SKU: orb1306150

Description

This novel small molecule apoptosis inhibitor functions by specifically targeting and inhibiting caspase-3 activity, thereby preventing programmed cell death. It is a valuable research tool for studying apoptotic pathways in both cellular and animal models of diseases such as neurodegeneration and ischemia-reperfusion injury.

Research Area

Cell Biology, Protein Biochemistry

Images & Validation

Key Properties

CAS Number54135-60-3
MW236.26
Purity97.80% (May vary between batches)
FormulaC13H16O4
SMILESC(C1C(=O)CCCC1=O)C2C(=O)CCCC2=O
TargetApoptosis,Caspase
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4.23 mM);DMSO:9 mg/mL (38.09 mM);H2O:0.1 mg/mL (0.42 mM)

Bioactivity

In Vitro
Apoptosis Inhibitor was identified as a novel inhibitor of apoptosis (programmed cell death) using an in vitro cell death assay system induced in human Fas-expressing WC8 cells by soluble human Fas ligand.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Alopecia, anti-Fas, Apoptosis, caspase-3, Caspase-3, chemotherapy, M 50054, M50054, M-50054, inhibit, Inhibitor, Hepatitis, Fas, Etoposide
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Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

M50054 (orb1306150)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 110.00
25 mg
$ 160.00
50 mg
$ 210.00
DispatchUsually dispatched within 3-5 working days
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