M47

SKU: orb1982662

Description

M47 is a selective CRY1 degrader that destabilizes and enhances nuclear degradation of the Cryptochrome 1 protein. It has been shown to extend lifespan in p53 knockout mouse models, facilitating research into circadian-related biology and cancers involving p53 mutations in both in vitro and in vivo studies.

Research Area

Cell Biology

Key Properties

• CAS Number: 890808-56-7
• MW: 471.93
• Purity: >99.99% (May vary between batches)
• Formula: C₂₈H₂₂ClNO₄
• SMILES: O=C(C=1OC2=CC=C3OC(C4=CC=C(Cl)C=C4)(C)CC(=O)C3=C2C1C)N5C=6C=CC=CC6CC5
• Target: p53,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

23601714