M443

SKU: orb1707022

Description

M443 is a potent and selective MRK inhibitor that blocks radiation-induced p38 and Chk2 activation. This small molecule is a valuable research tool for investigating DNA damage response pathways and has been utilized in both in vitro and in vivo cancer research models.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 1820684-31-8
• MW: 589.61
• Purity: 98.95% (May vary between batches)
• Formula: C₃₁H₃₀F₃N₇O₂
• SMILES: Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)C3CCCN(C3)C(=O)C=C)c2)cc(c1)C(F)(F)F
• Target: Others,MLK,Chk,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

92042851