M2N12

SKU: orb1309452

Description

M2N12

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 2376577-06-7
• MW: 393.83
• Purity: 98.70% (May vary between batches)
• Formula: C₂₀H₁₆ClN₅O₂
• SMILES: Cc1ccc(Cn2cc(CNC3=C(Cl)C(=O)c4cccnc4C3=O)nn2)cc1
• Target: Phosphatase,CDK
• Solubility: DMSO:8 mg/mL (20.31 mM)

Bioactivity

• Target IC50:
  CDC25C:0.09 μM|MCF-7 cells:4.71 μM|KB-VIN:6.81 μM|HBE:6.00 μM|KB:5.05 μM|MDA-MB-231 cells:4.63 μM|A549 cells:3.92 μM
• In Vitro:
  M2N12 has cytotoxic activity against five tumor cell lines and a normal cell line including A-549(IC50 = 3.92 μM), MDA-MB-231(IC50 = 4.63 μM), KB(IC50 = 5.05 μM), KB-VIN(IC50 = 6.81 μM), MCF-7(IC50 = 4.71 μM) and HBE(IC50 = 6.00 μM).
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CDK, CDC25C, Cyclin dependent kinase, cancer, A-549, Inhibitor, HBE, MCF-7, KB-VIN, inhibit, M2N12, M-2N12

Compound Identifiers

PubChem CID

139600304