M2 ion channel blocker-2

SKU: orb3173316

Description

M2 ion channel blocker-2 (Compound 10) is an inhibitor of the M2 ion channel. It effectively blocks both the wild type and mutant M2 (L27F and V27A) ion channels. This compound exhibits potent antiviral activity against HCoV-229E, with an EC50 of 4.7 μM for cytopathic effect, but shows no efficacy against influenza A virus. Additionally, M2 ion channel blocker-2 does not significantly inhibit hERG or cytochrome P450 enzymes (CYP1A2, CYP2C19, and CYP3A4).

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2260797-32-6
• MW: 205.35
• Formula: C₁₄H₂₃N
• SMILES: NC12CC3(C)C4(C)CC2CC4(C)C3(C)C1
• Target: SARS-CoV

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

SARS-CoV