M1001

SKU: orb1299493

Description

M1001 is a small molecule agonist that selectively activates the HIF-2α protein. It is a valuable research tool for studying hypoxia signaling pathways in both cellular and animal models, with applications in oncology and metabolic disease research.

Research Area

Cardiovascular Research, Epigenetics & Chromatin, Metabolism Research

Key Properties

• CAS Number: 874590-32-6
• MW: 327.4
• Purity: 100.00%
• Formula: C₁₇H₁₇N₃O₂S
• SMILES: O=S1(=O)N=C(Nc2ccccc2N2CCCC2)c2ccccc12
• Target: HIF,HIF/HIF Prolyl-Hydroxylase
• Solubility: DMSO:250 mg/mL (763.59 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (15.27 mM)

Bioactivity

• Target IC50:
  HIF2α:667 nM(Kd)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Hypoxia-inducible factors, Inhibitor, HEK293T, HIFs, HIFProlylHydroxylase, HIF-2α, HIF-PH, HIF/HIFProlylHydroxylase, HIF/HIF Prolyl-Hydroxylase, HIF/HIF ProlylHydroxylase, HIF ProlylHydroxylase, HIF Prolyl-Hydroxylase, HIF, inhibit, M1001, M-1001, M 1001, 786-O, chronic kidney disease

Compound Identifiers

PubChem CID

4905675