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(M)-AVI-4773

SKU: orb3210555

Description

(M)-AVI-4773 is an orally active inhibitor of the coronavirus MPro that can cross the blood-brain barrier, exhibiting an IC50 of 2.5 nM for SARS-CoV-2 MPro. In mouse models infected with MERS-CoV and SARS-CoV-2, (M)-AVI-4773 quickly demonstrates antiviral effects.

Images & Validation

Key Properties

CAS Number3111610-68-2
MW444.39
FormulaC23H14F2N6O2
SMILESO=C1C(=C(N(C(=O)N1C2=CN=CC3=CC=CC=C32)CC#C)C)N4N=NC=5C=C(F)C(F)=CC54
TargetVirus Protease,SARS-CoV

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information